I Ferrer Selected Research

Pick Disease of the Brain (Pick's Disease)

2/2013	Neuropathology of the hippocampus in FTLD-Tau with Pick bodies: a study of the BrainNet Europe Consortium.
10/2006	Glial fibrillary acidic protein is a major target of glycoxidative and lipoxidative damage in Pick's disease.
4/2006	Abnormal Sp1 transcription factor expression in Alzheimer disease and tauopathies.
6/2005	BetaII-tubulin and phospho-tau aggregates in Alzheimer's disease and Pick's disease.
8/2004	Selective PrP-like protein, doppel immunoreactivity in dystrophic neurites of senile plaques in Alzheimer's disease.
12/2002	Anti-tau phospho-specific Ser262 antibody recognizes a variety of abnormal hyper-phosphorylated tau deposits in tauopathies including Pick bodies and argyrophilic grains.
12/2002	Glycogen synthase kinase-3 is associated with neuronal and glial hyperphosphorylated tau deposits in Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration.
4/2001	Phosphorylated map kinase (ERK1, ERK2) expression is associated with early tau deposition in neurones and glial cells, but not with increased nuclear DNA vulnerability and cell death, in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration.
1/2001	Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in neurons and glial cells in tauopathies.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

I Ferrer Research Topics

Disease

38	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 01/2000
14	Amyloid Plaque 01/2016 - 05/2000
11	Tauopathies 02/2012 - 01/2001
10	Parkinson Disease (Parkinson's Disease) 09/2013 - 05/2000
9	Pick Disease of the Brain (Pick's Disease) 02/2013 - 01/2001
8	Dementia (Dementias) 01/2020 - 01/2000
8	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 11/2017 - 01/2000
7	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 09/2013 - 01/2001
6	Acquired CJD 11/2017 - 09/2001
6	Neoplasms (Cancer) 01/2016 - 12/2000
5	Prion Diseases (Transmissible Spongiform Encephalopathies) 01/2020 - 07/2002
5	Gliosis 10/2019 - 04/2004
5	Cognitive Dysfunction 01/2019 - 01/2006
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 12/2004
4	Neuroblastoma 10/2013 - 12/2000
4	Scrapie 08/2011 - 06/2002
4	Lewy Body Disease (Lewy Body Dementia) 10/2004 - 04/2001
4	Corticobasal Degeneration 12/2002 - 01/2001
3	Seizures (Absence Seizure) 01/2022 - 03/2002
3	Atrophy 10/2019 - 04/2005
3	Synucleinopathies 04/2008 - 04/2001
3	Frontotemporal Dementia (Semantic Dementia) 01/2007 - 01/2000
3	Muscular Diseases (Myopathy) 08/2005 - 12/2000
3	Olivopontocerebellar Atrophies (Olivopontocerebellar Atrophy) 06/2005 - 09/2001
3	Brain Diseases (Brain Disorder) 10/2004 - 01/2000
3	Sporadic Creutzfeldt-Jakob Disease 08/2004 - 01/2000
3	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 10/2003 - 03/2001
3	Necrosis 03/2002 - 12/2000
3	Ischemia 03/2001 - 08/2000
2	Fatal Familial Insomnia 11/2017 - 08/2004
2	Carcinoma (Carcinomatosis) 01/2016 - 10/2012
2	Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked) 11/2015 - 08/2013
2	Demyelinating Diseases (Demyelinating Disease) 08/2013 - 06/2005
2	Infections 08/2011 - 06/2002
2	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 06/2009 - 06/2007
2	Kuru 11/2008 - 08/2004
2	Myofibrillar Myopathy 02/2008 - 04/2005
2	Multiple System Atrophy 05/2005 - 04/2001
2	Infarction (Infarctions) 10/2003 - 03/2001
2	Brain Ischemia (Cerebral Ischemia) 05/2003 - 08/2000
2	Amyloid angiopathy 12/2002 - 01/2001
2	Medulloblastoma 10/2001 - 06/2001
2	Mitochondrial Diseases (Mitochondrial Disease) 03/2001 - 01/2001

Drug/Important Bio-Agent (IBA)

29	Proteins (Proteins, Gene)FDA Link 11/2017 - 01/2000
14	Amyloid (Amyloid Fibrils)IBA 02/2015 - 01/2001
12	Phosphotransferases (Kinase)IBA 02/2012 - 01/2001
10	Caspase 3 (Caspase-3)IBA 10/2004 - 12/2000
8	alpha-SynucleinIBA 04/2008 - 04/2001
7	Protein Isoforms (Isoforms)IBA 06/2009 - 01/2000
7	Mitogen-Activated Protein KinasesIBA 06/2007 - 01/2001
7	CaspasesIBA 10/2003 - 08/2000
6	Prion ProteinsIBA 01/2020 - 01/2000
6	SynaptophysinIBA 08/2011 - 01/2000
5	Messenger RNA (mRNA)IBA 11/2017 - 10/2006
5	AntibodiesIBA 02/2003 - 12/2000
4	SynucleinsIBA 01/2016 - 10/2004
4	UbiquitinIBA 02/2013 - 06/2005
4	Peptide Hydrolases (Proteases)FDA Link 01/2005 - 01/2000
4	JNK Mitogen-Activated Protein KinasesIBA 01/2005 - 01/2001
4	Fas Ligand Protein (Fas Ligand)IBA 06/2002 - 08/2001
3	Kainic Acid (Kainate)IBA 01/2022 - 03/2002
3	tau Proteins (tau Protein)IBA 10/2019 - 01/2005
3	PrionsIBA 11/2017 - 01/2000
3	EnzymesIBA 12/2016 - 01/2001
3	Mitochondrial DNA (mtDNA)IBA 08/2013 - 01/2001
3	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 06/2007 - 01/2001
3	Amyloid beta-PeptidesIBA 01/2006 - 01/2004
3	PrPSc ProteinsIBA 04/2005 - 01/2000
3	Cytochromes c (Cytochrome c)IBA 10/2003 - 03/2001
3	DNA (Deoxyribonucleic Acid)IBA 07/2002 - 04/2000
3	Glutamic Acid (Glutamate)FDA Link 03/2002 - 08/2000
3	Brain-Derived Neurotrophic Factor (BDNF)IBA 03/2001 - 01/2000
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 12/2016
2	LipidsIBA 09/2017 - 01/2000
2	ChemokinesIBA 12/2016 - 07/2015
2	Transcription Factors (Transcription Factor)IBA 07/2015 - 06/2007
2	Presenilin-1IBA 02/2015 - 02/2002
2	Amino Acids FDA Link 01/2014 - 04/2001
2	AcidsIBA 01/2014 - 02/2010
2	Methionine (L-Methionine)FDA Link 09/2013 - 08/2004
2	Valine (L-Valine)FDA Link 09/2013 - 08/2004
2	Membrane Proteins (Integral Membrane Proteins)IBA 10/2012 - 12/2000
2	Purinergic P1 Receptors (Adenosine Receptor)IBA 08/2011 - 08/2007
2	Codon (Codons)IBA 10/2010 - 08/2004
2	Protein AggregatesIBA 02/2008 - 04/2005
2	Glial Fibrillary Acidic ProteinIBA 10/2006 - 09/2003
2	TubulinIBA 06/2005 - 04/2005
2	ClusterinIBA 04/2005 - 10/2004
2	Type C PhospholipasesIBA 01/2005 - 10/2004
2	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 01/2005 - 10/2004
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 10/2004 - 09/2001
2	Carisoprodol (Soma)FDA LinkGeneric 04/2004 - 01/2000
2	Protein Kinase CIBA 02/2003 - 01/2001
2	Glycogen Synthase KinasesIBA 02/2003 - 12/2002
2	Synapsins (Synapsin I)IBA 07/2002 - 11/2001
2	Caspase 2IBA 09/2001 - 12/2000
2	HomocysteineIBA 01/2001 - 01/2000

Therapy/Procedure

3	Denervation 08/2017 - 12/2000
2	Therapeutics 11/2015 - 07/2000
2	Intraperitoneal Injections 03/2002 - 03/2002